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Product Details
MOTS-c is a focus for researchers studying retrograde mitochondrial communication. As a peptide encoded within mitochondrial DNA, it is investigated for its ability to translocate to the nucleus under metabolic stress and influence nuclear gene expression. Studies use MOTS-c to examine how mitochondria signal to the nucleus to coordinate adaptive metabolic responses in cellular models.
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Mitochondrial-to-Nuclear SignalingAMPK Activation & Glucose MetabolismIn metabolic research, MOTS-c is investigated for its activation of the AMPK pathway, a central regulator of cellular energy balance. Researchers study how MOTS-c influences glucose uptake, insulin sensitivity, and substrate utilization in skeletal muscle and adipose models, examining its role in metabolic homeostasis under varying energy conditions.
Recent studies have utilized MOTS-c to investigate adaptive responses to metabolic stress. By examining its expression patterns during energy demand, researchers explore the peptide’s role in cellular resilience, antioxidant gene regulation, and metabolic flexibility within preclinical frameworks.
Supplied as a purified, lyophilized powder, it is intended strictly for laboratory research; it is not for human or veterinary administration.
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Metabolic Stress & Exercise Models